<div class="content-intro"><p><a href="https://himalayas.app/companies/erasca">Erasca</a> is a clinical-stage precision oncology company focused on discovering, developing and commercializing medicines for the benefit of patients with cancer. Our programs take novel approaches to shutting down one of cancer’s most commonly mutated signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “<a href="https://himalayas.app/companies/erasca">Erasca</a>” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer.</p></div><p>The Clinical Trial Manager or Senior Clinical Trial Manager assists in the planning, implementation, and management of clinical studies from concept to completion. The position requires knowledge of clinical trial processes and prior experience in many aspects of trial execution from study start-up to study close-out, including assisting in the management of clinical vendors/CROs and assisting in the oversight of resources, budgets, contracts, and timelines.</p><h3>Essential Duties and Responsibilities: </h3><ul><li>Manage global clinical trials (Phase 1-3) in oncology indications, ensuring that studies are carried out in accordance with the clinical development plan, ICH-GCP, and FDA/other regulatory agency requirements. </li><li>Recruit global study sites and foster relationships with study investigators. </li><li>Participate in the process of site and vendor selection, qualification, and activation. </li><li>Develop Requests-for-Proposals and assist in vendor selection efforts. </li><li>Assist in review and negotiation of vendor contracts and study site clinical trial agreements. </li><li>Manage study vendors (e.g., CRO, IRT, laboratories, core ECG/imaging). </li><li>Monitor the progress of trials, including enrollment and clinical trial material inventory. </li><li>Review monitoring visit reports for completeness and adherence to the annotations.</li><li>Assist in packaging/labeling/distribution of clinical trial material. </li><li>Monitor and track biological samples for applicable analyses. </li><li>Provide progress updates to management and during program team meetings. </li><li>Assist in departmental budgeting, including accruals and projections. </li><li>Assist in development of protocols, consent forms, IRB/EC materials, and other trial documents. </li><li>Assist in development of Clinical SOPs. </li><li>Prepare/review/approve study materials such as CRFs, patient diaries, drug accountability forms, study and investigator manuals, project plans, and monitoring reports. </li><li>Assist in electronic case report form design and development.  </li><li>Assist in IRT design and development. </li><li>Participate in data cleaning activities and developing appropriate data outputs. </li><li>Understand and help fulfill the needs of other <a href="https:/